covid-19

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Clinell Universal Wipes are Effective Against COVID-19

Clinell Universal Wipes are the UK’s most trusted single-step detergent and disinfectant; ideal for use on both surfaces and non-invasive medical devices. Our patented near-neutral pH formula ensures exceptional material compatibility and is proven to kill at least 99.99% of pathogens after 10 seconds, norovirus within one minute and reduce instances of MRSA by 55%.

Clinell Universal Wipes are the NHS’ number 1 disinfectant wipe, used in 9 out of 10 NHS hospitals, now available for homes, schools and businesses. Kills 99.99% of bacteria and viruses from 20 seconds. Clinell Universal Surface Wipes kill up to 10x more bacteria and viruses than standard household disinfectants. Unlike pure disinfectant wipes, Clinell Universal Surface Wipes clean whilst they disinfect, helping remove dirt and soiling whilst boosting their germ-killing power. They get to get to work right away, proving effective from only 20 seconds. Despite all that cleaning and killing power, Clinell wipes are skin-friendly, dermatologically tested and kind to surfaces.

Clinell Universal Wipes are effective against the COVID-19 virus in 30 seconds. That means it’s important to understand contact time, contact time is the length of time the surface being disinfected must remain wet for the disinfectant to work. Clinell Universal Wipes have been tested according to EN14476 by an accredited, third-party laboratory. Test Reports for EN 14476 at 30 seconds show a pass using the SARS-CoV-2 virus in dirty conditions.

Clinell Wipes are designed for general disinfection and the cleaning of non-invasive medical devices and on surfaces. Clinell Wipes and are formulated to keep surfaces wet for the whole contact time. It’s important for users to remember to discard the wipe they’re using as it becomes dry or soiled. For our surface products, that means – unlike chlorine – that surfaces don’t need to be pre-cleaned before disinfecting. This reduces the opportunity for user error and makes sure we’re always delivering an effective dose of disinfectant.

To ensure that you and your family are protected from Covid-19 and other viruses and bacteria in 30 seconds, the Clinell Universal Wipes are the perfect choice for every homeowner and parent. Safe to use in food preparation areas the wipes are ideal for kitchens and cleaning down camping equipment.

 

 

 

Nayble 2021 year of hope

2021 Year of Hope

We’re finally about to leave this dreadful 2020 behind! This year was stacked with natural and man-made disasters, economic and mental collapse, bleeding healthcare and the untimely and unnecessary deaths of hundreds of thousands. No wonder we are all waiting for the year to end and find some peace of mind that it will all be over soon – and that 2021 will be better.

And hope, indeed, is what we have. Because throughout 2020, amazing advances have given hope that rose in science, technology, digital health, leadership and in basic human care and kindness. Anti-racist books topping the lists. More people wash hands than ever before. Neighbours caring, dogs adopted and people start searching for the real meaning of their lives. Although the current affairs always took the focus off of these positive consolidations, they were there and will stay with us in the future, giving hope not only for 2021 but for the years and decades way beyond it.

The scientific public has reacted to the news of the virus at an astonishing rate. Have you ever thought that the genome of a virus can be sequenced within 24 hours?! Not a single person would have bet on it before 2020, and still, we have seen the enormous and concentrated effort that was put into vaccine development over the past year. 

The global pandemic has put a spotlight on the life science industry, and, for the most part, it has stood up to the intensity of that glare.

In less than a year, biopharma and academia went from knowing nothing about SARS-CoV-2 to rolling out a new vaccine using brand-new technology to the world.

But the advent of this pandemic has also raised a lot of questions. Why, before 2020, had vaccines and infectious disease research been left at the back of the cupboard by so many? Meanwhile, rare diseases and cancer, typically much more profitable areas, have been sitting out on the countertop.

Experts had been warning about a major new epidemic or pandemic for years. SARS, Ebola, Zika and H1N1 should have raised their own alarms, but the surges of work to fight those diseases never led to sustained interest in infectious disease R&D.  

COVID-19 has left its fingerprints across everything in life sciences, whether directly or indirectly. Biotech IPOs have boomed this year, and not just those for biotechs hunting for COVID-19 drugs; in fact, most of those companies are going after typical oncology and rare disease targets. But as one of the only industries with strong growth amid the pandemic, biotech has seen a major bump in valuations and optimism.

Meanwhile, COVID-19 has also reshaped clinical trials: The rise and rise of the virtual model, so necessary during lockdowns to keep R&D moving in all disease areas, has become a present and future bet many pharmas and investors are now making.

The pandemic, coupled with the social justice movement, has fired up new interest in equitable drug research. Recruiting a truly diverse population for any trial has been a longstanding challenge, but COVID-19 brought diversification front and center; when patients of color are disproportionately affected by the disease—with more cases and more deaths—the same communities should be better tested in trials.Some companies did do so in their COVID-19 trials, although belatedly, but 2021 could be a year of true change.

Whatever the pandemic trajectory proves to be in 2021, it’s safe to say COVID-19 will have changed biopharma permanently, just as it has the rest of the world.

Pfizer-BioNTech vaccine - Nayble Ltd

COVID-19 Vaccine Developed by Pfizer and BioNTech

On 9 November, Pfizer became the first company in the world to complete Phase 3 of its coronavirus vaccine trials, which showed 90% efficacy. The news was followed earlier this week by an announcement from US pharmaceutical firm Moderna that its own vaccine candidate had a similarly promising efficacy of 94.5%. So far the UK government has ordered 40 million doses of the Pfizer-BioNTech jab – enough for 20 million people – and five million – for use on 2.5 million patients – of the Moderna one. The US and German companies say they will be able to produce 50 million doses this year and 1.3 billion in 2021.

The Pfizer-BioNTech vaccine has now proved 95% effective in preventing coronavirus and has met the safety criteria needed for emergency authorisation, the firms have said. Pfizer and BioNTech say they plan to submit the COVID-19 vaccine to the US regulator for emergency use approval “within days” after “no serious safety concerns” were reported.

The UK regulator, the Medicines and Healthcare products Regulatory Agency (MHRA), is also poised to fast-track authorisation of the vaccine after the government ordered enough for 20 million people.

Final efficacy analysis of the jab showed 95% were protected from the virus within 28 days of the first dose – up from when results of Phase 3 trials were shared last week. It also proved 94% effective among adults over the age of 65 – who are generally more vulnerable. There were no serious side effects, with only 2% of the 43,000 participants reporting a headache and 3.7% reporting fatigue, the companies said.

Pfizer and Moderna’s vaccine trials are two of around 12 worldwide, including one being developed by AstraZeneca and Oxford University, that are in the final stages of testing.

what country face mask -Nayble ltd

Which Countries Are Requiring Face Masks?

As the pandemic continues, more than half of the world’s countries are mandating the wearing of face masks in public. Is it helping to slow the spread of COVID-19?

Months into the pandemic, countries around the world are seeking to tighten public health policies to contain the spread of the new coronavirus disease, COVID-19 until there is an effective vaccine. With growing evidence that face coverings limit the virus’s transmission, more than one hundred countries have issued nationwide mask mandates. Others, including the United States and Brazil—which have the two highest confirmed case counts and death tolls—have decided against federal requirements, though some state and city officials have issued mask orders.

Face Masks usage was already common in some East Asian countries before the start of the pandemic. The first countries to set national mandates amid the coronavirus crisis were Vietnam and the Czech Republic, in mid-March. They have since become more common, although some European countries, including Lithuania and Slovakia, have lifted or loosened earlier mandates due to low case counts. In countries with limited mandates, masks are most commonly required on public transportation and in indoor spaces such as supermarkets and stores.

Nothing symbolizes our battle with the novel coronavirus like the face mask — it’s the most visible, humbling and contentious reminder of the deadly, invisible invader that we must live with until we find a vaccine.

In 2020, wearing a mask in cities like New York, London or Paris has gone from being a marker of the paranoid or vulnerable to the badge of the conscientious in the era of Covid-19. Even U.S. President Donald Trump put one on after previously disparaging them. Several studies suggest face coverings help — provided they’re properly made, maintained and worn — in limiting the spread of tiny exhaled particles carrying the coronavirus.

Still, not everyone’s wearing them.

The initial guidance from health officials was confusing, with many saying masks were only necessary for medical professionals or people exhibiting symptoms of infection. Or that only certain types of masks were effective. A shortage of supplies didn’t help either.

survey early on in the pandemic by Germany’s Max Planck Institute for Demographic Research found that mask-wearing in the West lagged far behind other precautions, such as keeping one’s distance from other people, regularly washing one’s hands and avoiding public transport.

Parting Ways

Facebook users in eight countries showed a lot of conformity in protective behaviours, except for mask wearing, where they diverged

But as the health advice evolved to emphasize wearing masks, so did some personal practices. Pollster YouGov has been surveying people’s self-reported mask-wearing habits globally and three distinct patterns emerge from the findings.

Early Adopters and Laggards

The trajectory of people who say they’ve worn a mask in public in the past two weeks to protect against Covid-19 falls into three main groups.

All of the areas that had high mask usage to start with, and where the practice of wearing face masks remained elevated in response to the pandemic, are in Asia.

That’s where the Covid-19 outbreak began and where the 2003 SARS outbreak is ingrained in people’s memories. Some places mandated face masks along the way. Japan gave cloth masks out to the public without imposing a draconian lockdown. That alone may have saved lives.

Places that had low mask usage initially, but where adoption subsequently rose, had different experiences of the outbreak. Yet there’s a unifying theme: Usage significantly rose after rules were established around wearing them.

High reported usage in France, where people needed a self-signed permission form to leave home at the height of lockdown, and Spain, where children weren’t allowed outside, reflects high death tolls, strict lockdowns and mandatory mask policies in those countries.

In the U.S., state politicians and the private sector are taking matters into their own hands: All but two states have at least some mask requirements, according to volunteer organization Masks4All, including New York, which accounts for almost a quarter of the country’s virus death toll. That’s a big reason why more than 70% of Americans report having worn a mask, according to YouGov. Meanwhile, restaurant and retail chains like Walmart Inc., McDonald’s Corp. and Starbucks Corp. are requiring them in their establishments.

Experiences in countries where the virus has remained relatively under control underline the power of clear policies over gentle nudging or relying on people’s common sense.

Germany, lauded for its cautious, consistent handling of the outbreak, saw adoption surge after introducing mask-wearing rules in April. There was a significant jump in Mexico after local governments mandated their use and gave out masks free. Singapore’s level shot up to 90%, from around 23% in early March, after the government ceased discouraging residents from donning face coverings, distributed them free and made them compulsory with a fine for failing to comply.

Then there are the countries where mask usage has stayed low.

In some places, such as Denmark, Finland and Norway, that’s easy to understand. Their Covid-19 outbreaks have been relatively contained, with among the lowest death tolls in the world. So low mask adoption doesn’t necessarily signal a policy failure. After all, masks are only one tool among many, and they’re by no means a panacea where they are in use.

Denmark’s health authority has discouraged mask wearing for healthy people going about their normal lives, questioning its effectiveness and saying it “can cause more harm than good.” There have been concerns that people who cover their mouth and nose may let down their guard or that face coverings may even become a vector for the virus if mishandled.

One Italian study, however, shows masks did encourage people to keep their distance. The U.S. CDC recommends wearing cloth masks as a preventative measure, while a WHO study found an apparent 85% reduction in infection risk when masked.

What’s striking about the low-mask-wearing group is that it includes Nordic neighbour Sweden, where a decision to keep much of society open as the outbreak worsened has led to a considerably higher mortality rate. Even as calls multiply for government measures such as rules on masks, Swedes aren’t taking it upon themselves to wear them.

The U.K. is even more confounding. It has the highest death toll in Europe, yet only 38% of respondents to YouGov’s latest tracker poll said they wore a mask. They cite many reasons, including staying home, inconsistent guidance and a failure of leaders to be role models. Prime Minister Boris Johnson was only recently pictured wearing a mask for the first time, in spite of overcoming a serious bout with Covid-19 in April.

Fear Factor

In general, face mask wearing has been the norm in places where fear is much greater.

When clear rules are introduced, such as last month’s public transport requirements in England and Scotland, Brits show they will comply. In fact, an Ipsos MORI survey in April and more recent results from YouGov in July found that though few Brits wear face coverings, a large majority support doing so or would wear them if the government mandated it. As part of efforts to jumpstart the economy, England will follow Scotland in requiring masks be worn in shops starting July 24.

Even rules can become politicized, though, as seen in the U.S. and Latin America, where the stakes are arguably the highest. Strongmen leaders who revel in tough-guy personas don’t generally like face masks: Brazil’s Jair Bolsonaro has watered down his own country’s mask law, while Trump’s resistance to wearing a mask (until his recent change of heart) has given succour to American anti-maskers who skew Republican.

All in all, masks are gaining momentum as countries reopen their economies while battling a virus that’s still very much with us. The looming challenge will be overcoming resistance from people who remain unconvinced by their merits or fatigue from those who feel Covid-19 is less of a threat.

As with changing social behaviour on safety issues, such as wearing a seatbelt or not driving when drunk, mask adoption will take time and effort. The limits of enforcement will likely lead to more carrot-and-stick approaches: Masks should ideally be free or widely distributed, government messaging should be clearer on where masks are required and why, and fines should be levied where necessary. Masks themselves should become more comfortable and fashionable to wear.

Until we have a vaccine or effective treatment, all countries should be on their guard. Once the mask straps start to loosen, they may do so for good.

Nayble covid-19 second wave

Fears of a second wave in the UK after a recent spike in Covid-19 cases

The Covid-19 pandemic is continuing across the globe, with over 27 million cases reported across 190 countries. Although countries across Europe previously appeared to have gained control of the virus through strict lockdown measures, many countries in this region are now concerned about experiencing a second wave. The second spike of Covid-19 cases was seen in the UK at the start of August, and while the new daily cases are currently increasing at a lower rate than was seen in the first wave, precautionary measures must be taken to prevent them from increasing any further.

GlobalData epidemiologists have shown the daily confirmed cases of Covid-19 in the UK from 1 March – 9 September. The first wave of the Covid-19 pandemic in the UK lasted from March until July, followed by approximately one month of control. Cases then started to rise again from the start of August. The UK’s first peak had a much steeper rise in daily confirmed cases within the first month. There were 147 new daily confirmed cases reported on 9 March and 4,906 new cases reported on 9 April, at an increase of 4,759 daily confirmed cases per month. A total of 1,113 new daily confirmed cases were reported on 9 August and 2,680 new cases reported on 9 September, at an increase of 1,567 daily confirmed cases per month. While a comparison of these two peaks has shown the second spike in cases rising at a lower rate than that of the first wave, the UK is no longer in the control phase of the pandemic. Preventative steps are required to prevent a continued rise in daily confirmed cases of Covid-19.

At the beginning of the pandemic, the UK experienced one of the worst outbreaks worldwide despite having a well-developed healthcare system. A lack of mass testing, contact tracing and delayed lockdown measures are all thought to be contributing factors toward the outbreak. After a ‘Stay at Home’ order was imposed by the government on 23 March, and two months of strict lockdown measures were implemented, the UK began to see signs of controlling the virus in mid-May. In July, the UK economy began to re-open again and students returned to schools and universities at the start of September. The recent spike in cases in the UK has promoted concerns that the country re-opened too soon.

Local lockdowns continue to be enforced throughout the UK as a method of controlling the virus. On 14 September, the UK government will issue a national ban on group gatherings of more than six people. Whether these controls are stringent enough to curb the spread of a second wave will become clear in the coming weeks. However, similar restrictions were re-introduced in Australia and Japan when those countries experienced a new spike in cases, and they are now undergoing a second wave that is much larger than the first. This emphasises the fact that the UK must not become complacent in its response to the pandemic. If the rate of new daily cases begins to increase further, controls will need to be put in place to prevent a larger second wave.

Social distancing: what you need to do?

To stop the spread of coronavirus (COVID-19), you should avoid close contact with anyone you do not live with.

  • try to stay at least 2 metres (3 steps) away from anyone you do not live with (or anyone not in your support bubble)
  • wash your hands with soap and water often – do this for at least 20 seconds
  • use hand sanitiser gel if soap and water are not available
  • wash your hands as soon as you get home
  • cover your mouth and nose with a tissue or your sleeve (not your hands) when you cough or sneeze
  • put used tissues in the bin immediately and wash your hands afterwards
  • do not touch your eyes, nose or mouth if your hands are not clean

Face coverings

If you can, wear something that covers your nose and mouth in places where it’s hard to stay away from other people.

There are some places where you must wear a face covering, such as:

  • on public transport
  • in shops
  • when you go to hospital appointments or visit someone in the hospital